Analysis of Clinical Characteristics and Prognostic Risk Factors of Mycoplasma pneumoniae Pneumonia in Adults of Different Age Groups
10.13241/j.cnki.pmb.2025.15.010
- VernacularTitle:不同年龄段成人支原体感染肺炎临床特征及其预后危险因素分析
- Author:
Jia ZHU
1
;
Tao-mei ZHANG
;
Qing-liu TAN
;
Cong-hui CHEN
;
Ya-nan MA
Author Information
1. 宁夏回族自治区第五人民医院感染性疾病科 宁夏石嘴山 753000
- Publication Type:Journal Article
- Keywords:
Mycoplasma pneumoniae;
Community-acquired pneumonia;
Age stratification;
Risk factors
- From:
Progress in Modern Biomedicine
2025;25(15):2472-2477
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical characteristics and prognostic risk factors of Mycoplasma pneumoniae pneumonia(MPP)in adults across different age groups,providing evidence for age-stratified management strategies.Methods:A retrospective analysis was conducted on 80 MPP patients admitted to the Respiratory Department of a hospital between January 2023 and December 2024.Patients were divided into three groups based on age:young adults(18-40 years),middle-aged adults(41-60 years),and elderly adults(≥ 61 years).Demographic features,clinical indicators,and mixed infections were analyzed.Univariate and multivariate Logistic regression were used to identify risk factors for disease severity.Results:The severity rate was significantly higher in the elderly group(41.2％)compared to the young adult group(7.1％)and middle-aged group(20.0％)(P=0.022).Elderly patients also exhibited significantly higher rates of underlying diseases(chronic lung disease:35.3％vs.3.6％in young adults),elevated inflammatory markers(C-reactive protein:68.3±19.5 mg/L vs.32.5±8.4 mg/L in young adults),mixed infections(52.9％vs.14.3％),and prolonged hospital stays(8.61±2.22 days vs.5.01±1.11 days)(P＜0.05).Multivariate analysis identified age(OR=1.79 per 10 years),chronic lung disease(OR=3.25),blood urea nitrogen ≥6 mmol/L(OR=2.44),and mixed infections(OR=4.26)as independent risk factors for severe MPP(P＜0.05).Conclusion:Clinical manifestations and prognoses of MPP in adults vary significantly across age groups.Elderly patients are characterized by high mixed infection rates,intense inflammatory responses,and renal function impairment,necessitating individualized monitoring and intervention strategies.
