The pathogenesis and treatment progress of chemotherapy-induced peripheral neuropathy
- VernacularTitle:化疗诱导的周围神经病变的发病机制及治疗进展
- Author:
Xin LU
1
;
Lin-zhuo QU
;
Yong WANG
;
Hong-jian GUAN
;
Yan-ling WU
Author Information
- Publication Type:Journal Article
- Keywords: chemotherapy-induced peripheral neuropathy; pe-ripheral neurotoxicity; chemotherapy-induced disease; drug-re-lated side effects and adverse reactions; traditional Chinese med-icine therapy; traditional Chinese medicine fumigation and wash-ing therapy
- From: Chinese Pharmacological Bulletin 2025;41(1):18-22
- CountryChina
- Language:Chinese
- Abstract: Chemotherapy-induced peripheral neuropathy(CIPN)refers to some symptoms and signs of peripheral nerve dysfunc-tion caused by using anti-tumor drugs,which is related to the dose of chemotherapy drugs.The pathogenesis of CIPN has not been fully defined,and the efficacy of existing therapeutic drugs and methods is limited.Therefore,it is of great scientific value and social significance to explore the pathogenesis of CIPN,de-velop new therapeutic drugs and methods,and solve the unmet clinical needs.This paper will elaborate on the pathogenesis of CIPN from the molecular and cellular levels,and review the treatment progress of CIPN,so as to provide reference for clinical treatment and direction for future research.
