Low vital capacity:an independent risk factor for functional outcome in SCI patients
10.3969/j.issn.1001-1242.2024.08.009
- VernacularTitle:低肺活量:影响脊髓损伤患者功能预后的独立危险因素
- Author:
Baijie XUE
1
;
Xia HE
;
Xiangbo WU
Author Information
1. 空军军医大学第一附属医院(西京医院)康复医学科,西安市,710032
- Publication Type:Journal Article
- Keywords:
spinal cord injury;
prognosis;
basic lung function;
related factors
- From:
Chinese Journal of Rehabilitation Medicine
2024;39(8):1149-1154,1161
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between basic lung function indicators and functional prognosis of spi-nal cord injury (SCI),and provide a basis for accurately judging the prognosis and improving the recovery ef-fect in the early clinical stage.Method:A retrospective analysis was made of 398 patients who met the inclusion and exclusion criteria in thedepartment of rehabilitation medicine of the first affiliated hospital of the air force military medical universityfrom June 2018 to May 2022. The data of patients' age,sex,body mass index (BMI),time from admission to injury,length of stay,ASIA classification and injury level,hematological indicators (white blood cell count,red blood cell count,hemoglobin concentration),and basic lung function test indicators at admission in-cluding tidal volume (VT),vital capacity (VC),forced vital capacity (FVC),forced expiratory volume in one second (FEV1),forced expiratory volume in one second/forced vital capacity (FEV1/FVC),peak expirato-ry flow (PEF),25％ forceful exhalation forced expiratory flow at 25％ of FVC exhaled(FEF25),forced expira-tory flow at 50％ of FVC exhaled(FEF50),forced expiratory flow at 75％ of FVC exhaled(FEF75),maximal voluntary ventilation (MVV),maximal voluntary ventilation/maximal predicted voluntary ventilation (MVV/MVVpre) were collected. The mean relative function gain (mRFG) of the modified Barthel index was used as the dependent variable,and the unit and multiple linear regression methods were used to identify the relevant factors affecting the prognosis of SCI patients,especially the underlying lung function indicators.Result:The single and multiple linear regression analysis showed that the prognosis of SCI patients was signifi-cantly related to the ASIA classification (B=11.064,P=0.019),length of stay (B=0.125,P=0.005) and VC (B=5.177,P=0.014). The cut-off value for VC judging the prognosis of SCI patients was 2.39L.Conclusion:Low VC is an independent risk factor for functional outcome in patients with SCI.The detection of basic lung function at the time of admission can help to judge the functional prognosis of patients with SCI. For the patients with VC below 2.39L,the prognosis is worse. Close attention should be paid to these patients,and more adequate rehabilitation treatments should be involved to maximize the improvement of pa-tients' daily living ability.
