Analysis of potential changes in symptom characteristics of breast cancer patients before and after chemotherapy and nursing countermeasures
10.3761/j.issn.0254-1769.2025.02.010
- VernacularTitle:乳腺癌患者化疗前后症状特征的潜在转变分析及护理对策
- Author:
Wanqin TIE
1
;
Xi ZHANG
;
Yongqi WANG
;
Yang XU
;
Xuefeng CHEN
;
Lu PAN
;
Siyu CHEN
Author Information
1. 750004 银川市 宁夏医科大学护理学院
- Publication Type:Journal Article
- Keywords:
Breast Cancer;
Postoperative Chemotherapy;
Latent Profile Analysis;
Latent Transition Analysis;
Root Cause Analysis;
Nursing Care
- From:
Chinese Journal of Nursing
2025;60(2):193-200
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the time-varying pattern of potential symptoms in breast cancer patient before and after chemotherapy,and further analyze its influencing factors,aims to provide reference for clinical nursing practice.Methods 233 cases of breast cancer in a tertiary A hospital in Ningxia from June to October,2023 were selected as the research subjects.By the general information questionnaire and the Chinese version of Anderson Symptom Assessment Scale,the potential change of symptoms of breast cancer patients undergoing chemotherapy 1-3 days before the first chemotherapy(T1,233 cases)and 7-14 days after the third or fourth chemotherapy(T2,225 cases)was analyzed.Results 225 cases of breast cancer patients completed 2 surveys,and their symptom characteristics before and after chemotherapy can be divided into 2 categories:a high symptom troubled group and a low symptom troubled group.The high-symptom troubled group has strong stability,and the probability of maintaining the original group is 85.20％,while the low-symptom troubled group is more inclined to change to the high-symptom troubled group,and the transition probability is 26.60％.Logistic regression analysis showed that the mass was located on the left side,and the patients who obtained disease knowledge mainly through the Internet were more likely to change from the high symptom troubled group to the low symptom troubled group,while the patients who were employed,with unsatisfactory sleep at night,and never exercised were more likely to change from the low symptom troubled group to the high symptom troubled group.Conclusion The symptoms of breast cancer patients before and after chemotherapy are heterogeneous.Patients who are on the job,have unsatisfied sleep at night and never exercise are more likely to change from the low-symptom troubled group to the high-symptom troubled group,which suggests that medical staff should identify potential high-risk groups at an early stage,and make full use of the predictive function of symptom characteristics to carry out individualized management based on the dynamic monitoring of symptoms according to different types of population characteristics,so as to reduce the burden of symptoms and improve their quality of life.
