Network Meta-analysis of traditional Chinese medicine compound prescription combined with western medications for treating coronary heart disease with depression
10.3969/j.issn.1673-9701.2025.01.012
- VernacularTitle:中药复方联合西药治疗冠心病合并抑郁的网状Meta分析
- Author:
Kexin WANG
1
;
Shaoqiang ZHANG
Author Information
1. 天津中医药大学研究生院,天津 301617
- Publication Type:Journal Article
- Keywords:
Efficacy combination;
Traditional Chinese medicine compound prescription;
Coronary heart disease;
Depression;
Network Meta-analysis
- From:
China Modern Doctor
2025;63(1):47-53
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the effectiveness of various traditional Chinese medicine(TCM)compound prescription combined with conventional western medications for treating coronary heart disease with depression through network Meta-analysis.Methods Search CNKI,Wanfang data,VIP,SinoMed,PubMed,Web of Science,Embase,Cochrane Library by computer.Randomized controlled trials of TCM compound prescription combined with conventional Western medications in the treatment of coronary heart disease with depression were collected from established to March 17,2024.The quality of the literatures was assessed using RoB 2.0 software,and network Meta-analysis was conducted using Stata 16.0 software.Results A total of 41 iteratures were included,involving 7 efficacy combinations.The results of the analysis showed that the highest clinical efficacy was found in the heat-clearing and tranquilizing category of TCM compound prescription+conventional western medicine[surface under the cumulative ranking curve(SUCRA)=79.4%],which significantly improved Hamilton depression scale scores(SUCRA=84.4%).The regulating qi type of TCM compound prescription+conventional western medicine significantly improved TCM symptoms(SUCRA=68.4%)and depression-related symptoms(SUCRA=94.8%).Conclusion Compared to using conventional Western medicines alone,the combined application of TCM compound prescription proves to be more effective,with regulating qi being crucial for treating this condition.
