Study on the consistency and diagnostic efficacy of kidney clear cell likelihood score v2.0 using high and low field intensity MRI
10.3969/j.issn.1002-1671.2025.09.019
- VernacularTitle:高、低场强MRI肾透明细胞癌可能性评分v2.0的一致性及诊断效能研究
- Author:
Xi LONG
1
;
Xiumei DU
1
;
Yingsi YANG
1
;
Weixiong FAN
1
;
Tianhui ZHANG
1
Author Information
1. 梅州市人民医院磁共振科,广东 梅州 514031
- Publication Type:Journal Article
- Keywords:
magnetic resonance imaging;
renal cell carcinoma;
clear cell likelihood score
- From:
Journal of Practical Radiology
2025;41(9):1512-1516
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the consistency and diagnostic efficacy of 1.5T and 3.0T MRI in the kidney clear cell likeli-hood score(ccLS)v2.0.Methods A retrospective collection was conducted on the data of 176 pathologically confirmed small renal mass(SRM).Two radiologists independently scored the MRI images using the ccLS v2.0.The Kappa test was used to assess inter-observer consistency,and receiver operating characteristic(ROC)curves were plotted to analyze the diagnostic efficacy.The area under the curve(AUC),sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NP V)were calculated.Results The inter-observer consistency for ccLS v2.0 score was good for 1.5T MRI and excellent for 3.0T MRI(Kappa values were 0.754 and 0.836,respectively).On 1.5T MRI examination,a ccLS≥4 points was identified as the optimal threshold,with AUC of 0.935 and 0.923 for the two radiologists,sensitivities of 92.45％and 88.68％,and specificities of 88.00％and 92.00％,respec-tively.For 3.0T MRI examination,using the same threshold,the AUC were 0.933 and 0.901,with sensitivities of 91.43％and 90.00％,and specificities of 78.57％and 78.57％for both radiologists.Conclusion The ccLS v2.0 demonstrates good consistency across high and low field intensity MRI,and a threshold of ccLS≥4 pionts provides high diagnostic efficacy for clear cell renal cell carcinoma(ccRCC).
