Repair of postoperative defects following orbital tumors resection using 3D-printed preformed titanium meshes: a multicenter long-term retrospective study
10.3760/cma.j.cn115330-20250606-00305
- VernacularTitle:使用3D打印预成型钛网修复眶区肿瘤术后缺损：一项多中心长期回顾性研究
- Author:
Tian YUAN
1
;
Tianfeng ZHAO
;
Xiaodong CHEN
;
Min XU
;
Zaixing WANG
;
Rui ZHENG
;
Shuo WU
;
Qintai YANG
;
Zhaohui SHI
Author Information
1. 中山大学附属第三医院耳鼻咽喉头颈外科 鼻眶颌颅底中心 变态反应（过敏）科，广州 510630
- Publication Type:Journal Article
- Keywords:
Orbit;
Reconstructive surgical procedures;
3D printing;
Preformed titanium mesh;
Naso-orbito-maxillary defect
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2025;60(9):1090-1096
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the long-term outcomes of using 3D-printed preformed titanium meshes in repair and reconstruction of orbital region.Methods:A retrospective analysis was conducted on patients with tumors invading the naso-orbito-maxillary region who underwent surgical resection and repair/reconstruction with 3D-printed preformed titanium meshes. The patients were collected at three medical centers (the Third Affiliated Hospital of Sun Yat-sen University, Xijing Hospital of Air Force Military Medical University, and Shenzhen Longgang District Ear, Nose and Throat Hospital) from 2016 to 2023. Tumor extent was evaluated radiologically, and the surgical approaches, reconstruction outcomes, surgical complications, and long-term follow-up results were analyzed.Results:A total of 46 patients from the three centers were included in this study, comprising 27 males and 19 females, with an average age of 51 years (range: from 13 to 86 years). Among them, 4 patients had benign tumors, while the remaining 42 had malignant tumors. The median follow-up duration was 60.7 months (range: from 19.0 to 75.0 months). Postoperatively, symmetrical globe position was achieved in 38 cases without significant diplopia; 4 cases exhibited enophthalmos without diplopia, and 4 cases had enophthalmos with diplopia. Twelve patients received preoperative radiotherapy, and 30 patients received postoperative radiotherapy. Six patients developed enophthalmos, and 6 experienced titanium mesh exposure after radiotherapy. Following treatment completion, 3 patients underwent repair using frontal flaps, 1 using a superficial temporal artery island flap, and 2 using free flaps. All remaining patients showed no postoperative infections, and their wounds healed normally.Conclusion:The application of 3D-printed preformed titanium mesh enables precise repair of postoperative defects in patients with naso-orbital tumors, facilitating reliable reconstruction of the orbital and facial contours with straightforward operation and dependable outcomes.
