Application of MXene-based hydrogels in wound repair
- VernacularTitle:MXene基水凝胶在创面修复领域的应用
- Author:
Rui HE
1
;
Chongyi LI
1
;
Ruiyao WANG
1
;
Dan ZENG
1
;
Daidi FAN
1
Author Information
- Publication Type:Journal Article
- Keywords: nano-functional materials; MXene; hydrogel; wound repair; biocompatibility; wound monitoring; sustained drug release
- From: Chinese Journal of Tissue Engineering Research 2025;29(16):3486-3493
- CountryChina
- Language:Chinese
- Abstract: BACKGROUND:MXene-based hydrogel is a kind of nano-composite multifunctional hydrogel material,which has broad application prospects in the field of chronic wound repair,such as diabetic foot,pressure sore,cancer,and traumatic ulcer.OBJECTIVE:To review the advantages of MXene-based hydrogels and their application and related action mechanism in wound repair.METHODS:The articles included in CNKI,VIP,PubMed,and Science Direct databases were searched from January 2010 to October 2023.The key words were"MXene,hydrogel,tissue engineering application,wound repair"in Chinese and"MXene,hydrogel,wound repair"in English.Finally,70 articles that met the criteria were selected for review.RESUILTS AND CONCLUSION:MXene-based hydrogels have excellent mechanical,electrical,photo-thermal properties,biocompatibility,and antibacterial effects in wound tissue engineering,and can be combined with other organic and inorganic substances to produce greater therapeutic effects in hydrogel.MXene-based hydrogels can be applied to skin wounds in combination with wound monitoring,drug delivery and release,and photothermal therapy.Despite some progresses in the design and preparation of MXene-based hydrogel composites,they are still in the fundamental research stage.There is a lack of clinical validation regarding their effectiveness and safety,but they hold great potential for development and application.
