Advances in the genetic research of Meniere's disease

VernacularTitle:梅尼埃病基因研究进展
Author: Mingwei XU ¹ ; Yu WANG ; Yuan YAO ; Qiong WU ; Qin ZHANG ; Jun YANG ; Yulian JIN ; Qing ZHANG
Author Information

1. 上海交通大学医学院附属新华医院耳鼻咽喉头颈外科上海交通大学医学院耳科学研究所上海市耳鼻疾病转化医学重点实验室(上海 200092)
Publication Type:Journal Article
Keywords: Familial Meniere's disease; Sporadic Meniere's disease; Candidate genes
From: Journal of Audiology and Speech Pathology 2025;33(5):479-484
CountryChina
Language:Chinese
Abstract: Meniere's disease represents an idiopathic inner ear disorder characterized by endolymphatic hy-drops.Currently,the research methods for identifying genes associated with this disease mainly involve first-genera-tion sequencing and second-generation sequencing.This article reviews research on the genetic study of Meniere's disease,mainly summarizing the candidate genes with repeated pedigree validation in familial Meniere's disease,as well as those frequently reported in sporadic Meniere's disease.