The influencing factors of hyperacusis in normal hearing population and the construction of a nomo-gram prediction model
10.3969/j.issn.1006-7299.2025.05.008
- VernacularTitle:听力正常人群发生听觉过敏的影响因素及列线图预测模型构建
- Author:
Yao CHENG
1
;
Qingchun PAN
1
;
Bei LI
1
;
Yuanling WANG
1
;
Jing ZHANG
1
;
Xiaoming TANG
1
Author Information
1. 川北医学院附属医院耳鼻咽喉头颈外科(南充 637000)
- Publication Type:Journal Article
- Keywords:
Hyperacusis;
Risk factors;
Nomogram;
Hearing
- From:
Journal of Audiology and Speech Pathology
2025;33(5):448-454
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors of auditory hypersensitivity in normal hearing population and build a risk nomogram model according to the results,so as to provide scientific basis for early identi-fication of high risk population and formulation of prevention strategy.Methods A total of 410 volunteers with nor-mal pure tone hearing were recruited from March to July 2024.The hyperacusis questionnaire(HQ)was used to as-sess the audiroty hypersensitivity of the subjects.The participants were divided into a training set(n=287)and a validation set(n=123)according to a ratio of 7∶3.Binary Logistic model was used to construct risk model and no-mogram.Receiver operating characteristic(ROC)curve,Hosmer-Lemeshow calibration curve,clinical decision curve(DCA)and clinical impact curve were used to verify the differentiation,accuracy and clinical applicability of the model,respectively.Results Among 410 participants,54(13.17%)had hyperacusis including 38(13.24%)in the training set amd 16(13.01)in the validation set.LASSO regression and Logistic regression analysis showed that tinnitus(OR=3.784,95%CI=1.627-8.804),HADS-A(OR=3.860,95%CI=1.503-9.913),HADS-D(OR=3.118,95%CI=1.249-7.785),migraine(OR=2.821,95%CI=1.147-6.937)and noise exposure histo-ry(OR=3.799,95%CI=1.715-8.416)were the influential factors for hyperacusis in participants with normal hearing.Conclusion The incidence of hyperacusis in normal hearing population is 13.17%.Tinnitus,HADS-A,HADS-D,migraine and noise exposure history are related to the occurrence of hyperacusis in normal hearing popula-tion.The risk prediction nomogram model based on the above factors has good differentiation and calibration degree.It can effectively predict the risk of hyperacusis in normal hearing people,and has certain clinical practicability.