Application of glucocorticoids in oral mucosal diseases
10.13591/j.cnki.kqyx.2025.09.013
- VernacularTitle:糖皮质激素在口腔黏膜病中的应用现状
- Author:
Minqian YING
1
;
Kaiyue LI
1
;
Chuanxia LIU
1
Author Information
1. 浙江大学医学院附属口腔医院口腔内科中心·浙江大学口腔医学院·浙江省口腔疾病临床医学研究中心·浙江省口腔生物医学研究重点实验室·浙江大学癌症研究院·口腔生物材料与器械浙江省工程研究中心,浙江 杭州(310000)
- Publication Type:Journal Article
- Keywords:
glucocorticoids;
oral mucosal diseases;
action mechanism;
efficacy;
adverse reactions
- From:
STOMATOLOGY
2025;45(9):713-720
- CountryChina
- Language:Chinese
-
Abstract:
Glucocorticoids possess potent anti-inflammatory and immunosuppressive properties,rendering them a common therapeutic option for oral mucosal diseases.The mechanisms of glucocorticoid action are diverse,encompassing both genomic and non-genomic effects.Given the ubiquitous presence of glucocorticoid receptors in nearly all human cells,their impact is widespread.While the effi-cacy of glucocorticoids is evident,prolonged or high-dose administration can lead to various adverse effects.Therefore,it is crucial to understand the mechanism of action and adverse reactions of glucocorticoids,master the indications and dosage of glucocorticoids in the treatment of oral mucosal diseases,and apply glucocorticoids correctly and reasonably in the diagnosis and treatment of oral mucosal diseases.At the same time,it is important to monitor the adverse reactions after medication and deal with them timely to ensure the safety of medication for patients.