Anaphylactic shock caused by an intravenous infusion of etimicin
10.3760/cma.j.cn114015-20210208-00182
- VernacularTitle:静脉滴注依替米星致过敏性休克
- Author:
Bobo PAN
1
;
Xiaohong XU
;
Xiaoyan LU
;
Yuena HUANG
;
Han ZHONG
;
Youqin DAI
Author Information
1. 中国科学院大学宁波华美医院药学部，宁波 315010
- Publication Type:Journal Article
- Keywords:
Anaphylaxis;
Shock;
Etimicin;
Drug-related side effects and adverse reactions;
Case report
- From:
Adverse Drug Reactions Journal
2021;23(12):661-663
- CountryChina
- Language:Chinese
-
Abstract:
A 54-year-old female patient was scheduled to undergo laparoscopic segmental resection for hepatic hemangioma. Thirty minutes before operation, an IV infusion of etimicin sulfate and sodium chloride injection 100 mg was given to prevent infection. After 2 minutes of medication, the patient developed general numbness, apathy, redness of the skin, cold sweating, and dyspnea. Her breath rate was 22 times per minute, heart rate was 110 beats per minute, blood pressure was 45/32 mmHg, and pulse oxygen saturation (SPO 2) was undetectable. Anaphylactic shock due to etimicin was considered. Etimicin was discontinued immediately and treatments such as oxygen inhalation, epinephrine, methylprednisolone sodium succinate, norepinephrine, and intravenous volume expansion were administered. Twenty minutes later, the patient′s symptoms were basically relieved, with breath rate 18 times per minute, heart rate 88 times per minute, blood pressure 108/60 mmHg, and SPO 2 0.99. Thirteen hours later, all symptoms disappeared.
