Correlation studies of histopathological features,clinical prognosis,and genomic mutation profiles in non-small cell lung cancer
10.13315/j.cnki.cjcep.2025.01.016
- VernacularTitle:非小细胞肺癌组织病理特征与临床预后、基因组突变谱的关联研究
- Author:
Lu HE
1
;
Zhiwen LI
;
Fanqing MENG
;
Yipin WANG
Author Information
1. 南京大学医学院附属鼓楼医院病理科,南京 210008
- Publication Type:Journal Article
- Keywords:
non-small cell lung cancer;
spread through air spaces;
tumor budding;
IASLC grading system;
driver gene mutations;
literature review
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(1):99-104
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer represents as one of the most prevalent malignant tumors globally,necessitating the urgent identification of additional biomarkers to facilitate precise stratified treatment and elevate its survival rates.Previous studies have focused on the correlation between the histopathological characteristics,driver gene mutations,and progno-sis of non-small cell lung cancer(NSCLC),with the aim of predicting the potential molecular background,treatment efficacy,and possible clinical outcomes of patients from the morphological perspective.This article aims to briefly sum-marize the advancements in emerging histopathological indicators of NSCLC,and discuss their implications for guiding the prognosis of this disease.
