Research status of traditional Chinese medicine and its active ingredients in the treatment of prostate cancer by interfering with Wnt/β-catenin signaling pathway
10.13699/j.cnki.1001-6821.2024.21.025
- VernacularTitle:中药及其有效成分干预Wnt/β-catenin信号通路治疗前列腺癌的研究现状
- Author:
Sheng-long LI
1
;
Yong-qiang ZHAO
;
Da-cheng TIAN
;
Gang-gang LU
;
Yuan-bo ZHAO
;
Guang-wei JIN
;
Mei-sheng GONG
;
Hui LI
;
Yun-peng JIA
;
Yong-lin LIANG
Author Information
1. 甘肃中医药大学中西医结合学院,甘肃兰州 730000
- Publication Type:Journal Article
- Keywords:
prostate cancer;
Wnt/β-catenin;
signaling pathway;
traditional Chinese medicine;
active ingredient;
research status
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(21):3191-3195
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine and its active ingredients have significant advantages in treating prostate cancer(PCa),and can complement the shortcomings of Western medicine,improving the quality of life for patients.This article reviews the research progress of traditional Chinese medicine and its effective ingredients in intervening in Wnt/β-catenin pathway to treat PCa,summarizing that the main effective ingredients in traditional Chinese medicine for preventing and treating PCa through this pathway are flavonoids,terpenes,alkaloids,phenols,and other compounds;the main traditional Chinese medicine formulas include Guben Qingyuanfang,Yishen Tongpang granules,etc,and discusses the mechanisms of action of these traditional Chinese medicines and their effective ingredients in intervening in this pathway to prevent and treat PCa,in order to provide a reference for the precise treatment of PCa and the application of traditional Chinese medicine research.
