Predictive value of MRA combined with CTA for neurological function in elderly patients with cerebral infarction
10.3969/j.issn.1009-0126.2024.12.015
- VernacularTitle:磁共振血管成像结合CT血管造影对老年脑梗死患者神经功能预后的预测价值分析
- Author:
Jian TAO
1
;
Lei HAN
1
;
Dongyang YU
1
;
Zhengyu ZHAO
1
;
Haifeng LU
1
;
Yong LIU
1
;
Chunsheng YANG
1
Author Information
1. 223002 淮安市第二人民医院影像科
- Publication Type:Journal Article
- Keywords:
brain infarction;
magnetic resonance angiography;
prognosis;
forecasting
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(12):1452-1456
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the predictive value of magnetic resonance angiography(MRA)combined with CT angiography for the prognosis of neurological function in elderly patients with cerebral infarction and its influencing factors.Methods A total of 102 elderly patients with cere-bral infarction admitted to our hospital from April 2020 to August 2023 were recruited,and ac-cording to the modified Rankin scale(mRS),they were divided into good prognosis group(mRS score≤3,66 patients)and poor prognosis group(mRS score＞3,36 patients).Their clinical data were collected.The stenosis rate of the lesion site was examined by MRA,and the Alberta stroke program early CT score(ASPECTS)was semi-quantitatively evaluated with CT angiography ex-amination.Multivariate logistic regression analysis was used to identify the influencing factors for poor neurological prognosis.ROC curve was plotted to analyze the predictive value of MRA com-bined with CT angiography for the prognosis.Results Advanced age,higher NIHSS score,larger white blood cell and neutrophil counts,and higher homocysteine level were observed in the poor prognosis group than the good prognosis group(P＜0.01).The poor prognosis group had signifi-cantly higher stenosis rate and lower ASPECTS than the good prognosis group(P＜0.01).Multi-variate logistic regression analysis showed that NIHSS score,white blood cell count,neutrophil count,stenosis rate and ASPECTS were independent risk factors for poor prognosis of neurologi-cal function in elderly patients with cerebral infarction(P＜0.05,P＜0.01).The AUC value of stenosis rate,ASPECTS and their combination in predicting poor prognosis of neurological func-tion in elderly patients with cerebral infarction were 0.745(95％CI:0.645-0.844)and 0.711(95％CI:0.598-0.824),and 0.891,respectively.The AUC value of the combination was the highest,with a sensitivity of 87.76％and a specificity of 63.65％.Conclusion NIHSS score,white blood cell count,neutrophil count,stenosis rate and ASPECTS are independent risk factors for poor prognosis of neurological function in elderly patients with cerebral infarction.The combina-tion of stenosis rate and ASPECTS based on MRA and CT angiography has the highest predictive value.
