Research status of circulating tumor DNA in colorectal cancer
10.13699/j.cnki.1001-6821.2024.21.024
- VernacularTitle:循环肿瘤DNA在结直肠癌中的研究现状
- Author:
Shao-bo MO
1
;
Yun FENG
;
Jun-jie PENG
;
Hai ZOU
Author Information
1. 复旦大学附属肿瘤医院大肠外科,上海 200032;复旦大学上海医学院肿瘤学系,上海 200032
- Publication Type:Journal Article
- Keywords:
circulating tumor DNA;
colorectal cancer;
minimal residual disease;
early diagnosis;
treatment monitoring
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(21):3186-3190
- CountryChina
- Language:Chinese
-
Abstract:
Circulating tumor DNA(ctDNA)is emerging as a pivotal technology in the diagnosis and therapeutic management of colorectal cancer(CRC).Serving as a liquid biopsy biomarker,ctDNA offers genetic insights into tumors,encompassing mutations,methylation patterns,and more,thereby holding significant promise for early detection,treatment response monitoring,and prognostic evaluation.This review comprehensively outlines the research strides in ctDNA pertaining to CRC,encompassing early-stage screening and diagnosis,minimal residual disease surveillance,treatment response tracking and prognostic status.
