Ataxia induced by dexzopiclone
10.3760/cma.j.cn114015-20201128-01184
- VernacularTitle:右佐匹克隆致共济失调
- Author:
Huiping WEN
1
;
Xinzhi LYU
;
Yiling CHEN
;
Xuejuan HUANG
;
Wenhui HUANG
Author Information
1. 联勤保障部队第九〇九医院消化内科，福建省漳州市 363000
- Publication Type:Journal Article
- Keywords:
Hypnotics and sedatives;
Ataxia;
Dyskinesia, drug-induced;
Dextrzopiclone
- From:
Adverse Drug Reactions Journal
2021;23(5):271-272
- CountryChina
- Language:Chinese
-
Abstract:
A 68-year-old male patient with severe active ulcerative colitis developed sleep disorder after using hormone pulse therapy. He received dexzopiclone 3 mg orally once a night to improve sleep. On the next day of medication, the patient developed ataxia symptoms such as dizziness, head drooping, and body skewing when walking, etc. The patient had a history of Parkinson′s syndrome and treatment effect of levodopa and benserazide hydrochloride was good. Dyskinesia caused by levodopa and benserazide hydrochloride were suspected. Then the drug was stopped and symptomatic treatments were given for 3 days, but his symptoms were not improved. After consultation with the neurologist, the patient was diagnosed as having ataxia, which was suspected to be related to dextrzopiclone. Four days after dextrzopiclone withdrawal, the patient′s symptoms were improved obviously. The patient resumed to use levodopa and benserazide hydrochloride before discharge and the ataxia symptoms above mentioned did not recur.
