Strategies and thoughts on comprehensive treatment of gastric cancer
10.3760/cma.j.cn115610-20250205-00044
- VernacularTitle:胃癌综合治疗策略与思考
- Author:
Zekuan XU
1
;
Xiaofeng CHEN
;
Yitong TIAN
Author Information
1. 南京医科大学第一附属医院胃肿瘤中心 普通外科，南京 210029
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Targeted therapy Precision treatment;
Combined therapy;
Comprehensive treatment
- From:
Chinese Journal of Digestive Surgery
2025;24(3):317-325
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer is a highly lethal malignant tumor, with early diagnosis being difficult and treatment outcomes influenced by multiple factors. In recent years, comprehensive treatment approach, incorporating surgery, chemotherapy, radiotherapy, targeted therapy, and immuno-therapy, has significantly improved efficacy. The advantages of comprehensive treatment are most important in patients with locally advanced and metastatic gastric cancer. For locally advanced cases, surgery serves as the core treatment, with various therapeutic modalities applied during the peri-operative period to enhance surgical outcomes. For metastatic patients, drug therapy is the primary method, supplemented by local treatments to achieve the best benefit. With the understanding of the molecular mechanisms underlying gastric cancer development, the use of molecular biomarkers for prognostic stratification and guidance for targeted therapy or immuno-therapy has become a crucial aspect of comprehensive treatment. Based on the latest research advancements, the authors discuss comprehensive treatment strategies for gastric cancer at different stages, offering insights into impro-ving efficacy and prognosis.
