The anatomical pathogenesis and treatment strategy of gastroesophageal reflux disease
10.3760/cma.j.cn115610-20241017-00456
- VernacularTitle:胃食管反流病发生的解剖学基础及手术治疗策略
- Author:
Ming ZHENG
1
;
Yimin E
;
Chen LU
;
Fanggui XU
;
Tianyu LIU
;
Chunzhao YU
Author Information
1. 南京医科大学附属逸夫医院普通外科,南京 211112
- Publication Type:Journal Article
- Keywords:
Gastroesophageal reflux disease;
Hiatal hernia;
Pathogenesis;
Anti-reflux surgery;
Anatomy;
Efficacy
- From:
Chinese Journal of Digestive Surgery
2024;23(11):1465-1470
- CountryChina
- Language:Chinese
-
Abstract:
Gastroesophageal reflux disease (GERD) is a prevalent disorder within the digestive system, characterized by the regurgitation of gastric and duodenal contents into the esophagus or extraesophageal regions, leading to a spectrum of clinical symptoms. The esophagogastric junction serves as the principal area for anti-reflux function, with anomalies in anatomical structures including the lower esophageal sphincter, the crural diaphragm, the phrenoesophageal ligament, and the angle of His as significant factors in the development of GERD. Reconstructive and reparative surgeries based on above anatomical structures are effective methods for treating GERD, with a variety of surgical approaches each offering distinct advantages and focal points. The authors elucidate the anatomical pathogenesis and rational selection of surgical methods for GERD.