Effectiveness of active screening combined with intervention in CRE pre-vention and control in medical institutions:a Meta-analysis
10.12138/j.issn.1671-9638.20245446
- VernacularTitle:医疗机构开展主动筛查联合干预对CRE防控效果的Meta分析
- Author:
Xiao-qin WU
1
;
Feng GUO
1
;
Li-ran SHI
1
;
Jin LI
1
;
Hong-xia KAN
1
;
Ai-ying LI
1
Author Information
1. 江苏省徐州市贾汪区人民医院感染管理科,江苏 徐州 221011
- Publication Type:Journal Article
- Keywords:
carbapenem-resistant Enterobacterales;
active screening;
healthcare-associated infection;
Meta-analysis
- From:
Chinese Journal of Infection Control
2024;23(12):1537-1543
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the effectiveness of active screening in the prevention and control of healthcare-associated infection(HAI)with carbapenem-resistant Enterobacterales(CRE)in Chinese medical in-stitutions through Meta-analysis.Methods Studies on active screening combined with intervention for CRE in Chi-nese medical institutions published from the establishment of databases to April 2024 were retrieved from Wanfang Database,VIP database,China National Knowledge Infrastructure,China Biomedical Literature Database,Em-base,PubMed,Cochrane Library,and Web of Science.Meta-analysis was performed to study the effectiveness of active screening combined with intervention in CRE prevention and control.Results A total of 14 literatures were included in the analysis,including 12 non-randomized controlled studies and 2 randomized controlled studies.Meta-analysis results showed that active screening and timely intervention measures against CRE in hospitalized patients could effectively reduce the incidence of HAI with CRE(relative risk[RR]=0.51,95%CI[0.43,0.61],P<0.05).Conclusion Active screening combined with intervention for CRE among hospitalized patients can effectively reduce the risk of CRE cross infection in hospitals.