The application value of paediatric age-adjusted shock index in children with sepsis and septic shock
10.3760/cma.j.issn.1673-4912.2025.07.004
- VernacularTitle:儿童年龄调整休克指数在脓毒症及脓毒性休克患儿中的应用价值
- Author:
Wei LI
1
;
Haiyan GE
1
;
Shuang LIU
1
;
Siyuan HUANG
1
;
Jing CHEN
1
;
Ning LI
1
;
Xiuxiu LU
1
;
Dong QU
1
Author Information
1. 首都医科大学附属首都儿童医学中心重症医学科，北京 100020
- Publication Type:Journal Article
- Keywords:
Paediatric age-adjusted shock index;
Sepsis;
Compensatory septic shock;
Decompensated septic shock
- From:
Chinese Pediatric Emergency Medicine
2025;32(7):500-503
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of paediatric age-adjusted shock index（SIPA）in early identification of septic shock in children，and to evaluate the relationship between SIPA and disease severity and prognosis.Methods:The infected children admitted to the department of critical care medicine of the Children's Hospital Affiliated to Capital Institute of Pediatrics from May 2023 to July 2024 were collected. Dynamic assessment was performed 0 to 6 hours after admission. Patients diagnosed with sepsis without septic shock were classified as the sepsis group and those diagnosed with sepsis with septic shock were classified as the septic shock group. According to whether the blood pressure of the children decreased，they were divided into two groups：compensated septic shock group and decompensated septic shock group. The difference of SIPA among the three groups was analyzed，and the predictive value of SIPA on case fatality rate，lactate level，pediatric critical illness score，ventilator utilization rate and length of hospital stay were analyzed.Results:Among 203 children with sepsis，112 were males and 91 were females. There were 146 cases in the sepsis group，37 cases in the compensated septic shock group and 20 cases in the decompensated septic shock group. There was no significant difference between the three groups in gender（ P>0.05），but there was a statistically significant difference in age（ χ 2=32.905， P<0.001）. There was no significant difference in age between the sepsis group and the compensated septic shock group（ P>0.05）. The age of sepsis group and decompensated septic shock group，compensated septic shock group and decompensated septic shock group were statistically significant（ χ 2=29.431， P<0.001； χ 2=19.764， P=0.001）. The proportion of increased SIPA was statistically different among the three groups，with both the compensated septic shock group and the decompensated septic shock group being higher than the sepsis group（ χ2=20.383， P<0.001； χ2=33.600， P<0.001）. The decompensated septic shock group was higher than the compensated septic shock group（ χ2=6.555， P=0.01）. SIPA was correlated with case fatality rate，lactate level，pediatric critical illness score，ventilator use rate and length of stay of the children，with statistically significant differences（ P<0.05）. Conclusion:The increase of SIPA can be used for the early identification of septic shock in children，and it has a certain early warning value for the prognosis assessment of sepsis and septic shock.
