Clinical features and short-medium term follow-up of children with severe multisystem inflammatory syndrome
10.3760/cma.j.issn.1673-4912.2025.01.008
- VernacularTitle:儿童重症多系统炎症综合征临床特征及中短期随访分析
- Author:
Yue LIU
1
;
Jian ZHANG
1
;
Biru LI
1
;
Botao NING
1
;
Fang ZHANG
1
;
Teng TENG
1
;
Hong REN
1
Author Information
1. 上海交通大学医学院附属上海儿童医学中心重症医学科200127
- Publication Type:Journal Article
- Keywords:
Children;
Multisystem inflammatory syndrome;
Clinical features;
Short and medium term follow-up
- From:
Chinese Pediatric Emergency Medicine
2025;32(1):38-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze and summarize the clinical features and short-medium term follow-up results of children with multisystem inflammatory syndrome（MIS-C）following coronavirus infection.Methods:The data of six children with MIS-C admitted to the Intensive Care Unit of Shanghai Children's Medical Center from January to March 2023 were retrospectively analyzed.Results:All six cases were in shock，requiring vasoactive drugs，and one case required invasive mechanical ventilation.All the six patients had multiple organ function injury and increased inflammation indicators.After admission，they received organ support，glucocorticoids and gamma globulin treatment.Two patients were treated with biological agents.Both organ function and inflammation indicators showed significantly improvement after therapy.Six patients had mild coronary artery widening.All patients had good prognosis following short-medium term follow-up.Conclusion:Children with severe MIS-C may suffer life-threatening hemodynamic instability.Timely assessment，active anti-inflammatory and organ support therapy can obtain favorable prognosis.
