Analysis of influencing factors of intestinal obstruction after laparoscopic radical resection of colorectal cancer
- VernacularTitle:腹腔镜结直肠癌根治术后发生肠梗阻的影响因素分析
- Author:
Yingchang CAI
1
;
Wenchao CHEN
1
;
Jiang GONG
1
Author Information
- Publication Type:Journal Article
- Keywords: colorectal cancer(CRC); laparoscopic radical resection of colorectal cancer(LRRCC); postoperative intestinal obstruction(IO); influencing factor
- From: China Journal of Endoscopy 2025;31(6):32-38
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the influencing factors of intestinal obstruction(IO)in patients with laparoscopic radical resection of colorectal cancer(LRRCC).Methods From March 31,2021 to March 31,2024,clinical data of 389 patients with colorectal cancer(CRC)were retrospectively selected.According to whether IO occurred during their postoperative hospitalization,they were divided into the IO group with IO(68 cases)and the non-IO group without IO(321 cases).The clinical data of IO group and non-IO group were compared and multivariate Logistic regression analysis was used to study the influencing factors of IO in CRC patients undergoing LRRCC.Results The proportions of patients with TNM stage Ⅲ,lymph node metastasis,preoperative anemia,preoperative hypoproteinemia,history of abdominal surgery,preoperative IO,intraoperative fistula,LRRCC with left hemicolectomy(LH),LRRCC with right hemicolectomy(RH),and postoperative abdominal infection in the IO group were higher than those in the non-IO group,the differences were statistically significant(P<0.05).Multivariate Logistic regression analysis showed that TNM stage Ⅲ(OR＾=1.872,95%CI:1.253～2.798),lymph node metastasis(OR＾=1.808,95%CI:1.181～2.766),preoperative anemia(OR＾=1.900,95%CI:1.051～3.435),preoperative hypoproteinemia(OR＾=1.642,95%CI:1.143～2.360),history of abdominal surgery(OR＾=1.704,95%CI:1.118～2.597),preoperative IO(OR＾=1.857,95%CI:1.064～3.240),intraoperative fistula(OR＾=1.696,95%CI:1.085～2.651),LRRCC with LH(OR＾=1.084,95%CI:1.012～1.161),LRRCC with RH(OR＾=1.164,95%CI:1.070～1.267),postoperative abdominal infection(OR＾=1.904,95%CI:1.019～3.558)were all independent risk factors for IO in patients with CRC after LRRCC(P<0.05).Conclusion TNM stage Ⅲ,lymph node metastasis,preoperative anemia,preoperative hypoproteinemia,history of abdominal operation,preoperative IO,LRRCC with LC,LRRCC with RH,intraoperative fistula and postoperative abdominal infection are independent risk factors for IO in CRC patients after LRRCC.Clinically,relevant high-risk CRC patients can be treated accordingly to reduce the risk of IO.
