Research progress of thyroid nodule in pregnancy

VernacularTitle:妊娠期甲状腺结节研究进展
Author: Chenchen WANG ¹ ; Tayier RISHALAITI ¹ ; Yuming ZHU ¹ ; Muhetaer DAWURENI ¹ ; Qin LIN ¹
Author Information

1. 新疆维吾尔自治区疾病预防控制中心（健康危害因素监测与控制所），乌鲁木齐　830011
Publication Type:Journal Article
Keywords: Iodine; Pregnant women; Thyroid nodules
From: Chinese Journal of Endemiology 2025;44(11):937-941
CountryChina
Language:Chinese
Abstract: Thyroid nodules (TNs) are defined as discrete lesions within the thyroid gland. Pregnancy, as a unique physiological stage, presents challenges for both clinicians and pregnant women when TNs are detected. Epidemiological studies have shown that the occurrence and development of TNs are closely related to hormonal changes during pregnancy, geographical location, and iodine intake. Thyroid ultrasonography is the best imaging method for evaluating TNs in pregnant women, which requires combined screening with serological diagnosis and multidisciplinary consultation (clinical endocrinologists, thyroid surgeons, and gynecologists, etc.) to discuss treatment indications, methods, and appropriate timing. Meanwhile, monitoring and follow-up during pregnancy should be conducted to assess the prognosis of both the mother and the fetus. This article focuses on reviewing the relevant research progress of TNs during pregnancy, and provides references for diagnosis, intervention, and treatment of TNs in the gestational period.