Research progress of long non-coding RNA in oral squamous cell carcinoma
10.11904/j.issn.1002-3070.2025.03.011
- VernacularTitle:长链非编码RNA在口腔鳞状细胞癌中的研究进展
- Author:
Xu WU
1
;
Leheibateer DE
;
Lintai DA
;
Nite SU
;
Jun LIU
Author Information
1. 呼和浩特市口腔医院(内蒙古自治区口腔医院)口腔颌面外科(呼和浩特 010000);呼和浩特市第二医院放射科
- Publication Type:Journal Article
- Keywords:
Oral squamous cell carcinoma;
Long non-coding RNA;
Epigenetic;
Tumor immune microenvironment;
Tumor drug resistance
- From:
Practical Oncology Journal
2025;(3):251-255
- CountryChina
- Language:Chinese
-
Abstract:
Oral cancer is one of the most common malignant tumors in the head and neck,with approximately 90%of oral cancer being squamous cell carcinoma.Oral squamous cell carcinoma(OSCC)has a high degree of malignancy and a poor prognosis,posing a serious threat human health.The occurrence and development of OSCC are relatively complex,influenced and regulated by multiple factors and levels,and the molecular mechanisms is currently not fully understood.Long non-coding RNA(lncRNA)can exert various biological functions by regulating gene expression and function at the transcriptional,translational,and post-translational lev-els.The occurrence and development of OSCC involve the abnormal expression of lncRNA.Therefore,this article reviews the relevant research on the function and molecular mechanisms of lncRNA in OSCC,in order to provide a reference for future studies.
