The Influence of Boundary Condition Changes of Inner and Outer Walls of Osteon on Fluid Flow Characteristics:A Finite Element Study
10.16156/j.1004-7220.2025.03.018
- VernacularTitle:骨单元内壁和外壁边界条件变化对其内间隙液流动特性影响的有限元研究
- Author:
Weilun YU
1
;
Xiuying LIU
;
Qiong WANG
;
Yuan YAO
;
Yubo GUO
;
Ning QU
;
Xiaogang WU
;
Haoyu FENG
;
Zhiqiang LI
Author Information
1. 山西白求恩医院骨科,太原 030024;吉林医药学院生物医学工程学院,吉林吉林 132013;太原理工大学生物医学工程学院,太原 030024
- Publication Type:Journal Article
- Keywords:
boundary condition;
osteon;
fluid flow;
pulsatile blood pressure;
pore pressure
- From:
Journal of Medical Biomechanics
2025;40(3):656-662
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of fluid flow within loaded osteons under different boundary conditions.Methods The COMSOL Multiphysics software was used to establish a three-dimensional(3D)finite element model of osteons with different boundary conditions,and the variation rules of pore pressure and flow velocity of osteons under different inner wall pulsating blood pressures and outer wall elastic constraint conditions were analyzed.Results As the pulsatile blood pressure inside the osteon increased from 0 mmHg(1 mmHg=0.133 kPa)to 300 mmHg,the peak pore pressure within the osteon correspondingly increased from 26 kPa to 68 kPa.As the elastic constraint on the outer wall of osteons changed from being completely elastic to completely constrained,the peak pore pressure within osteons increased from 15 kPa to 26 kPa,and the peak flow velocity increased from 0.04 um/s to 0.07 um/s.Conclusions This study reveals the influence laws of changes in boundary conditions such as the pulsatile blood pressure on the inner wall and the elastic constraint on the outer wall of osteons on fluid flow characteristics within loaded osteons.These findings are conducive to a deeper understanding of the mechanical response mechanisms of bone tissues in both physiological and pathological states,and provide an important theoretical basrs for further researches on bone mechanotransduction.
