Biomechanical Responses of Corneas after Small Incision Lenticule Extraction Based on Personalized Parameters of the Human Eye
10.16156/j.1004-7220.2025.03.029
- VernacularTitle:基于个性化人眼参数SMILE术后角膜生物力学响应分析
- Author:
Xinchao WANG
1
;
Lihua FANG
1
;
Jixi GUO
1
;
Yi ZHANG
1
;
Xuyang ZHANG
1
;
Mingzhe WANG
1
Author Information
1. 南昌航空大学江西省光电信息感知技术与仪器实验室,南昌 330063
- Publication Type:Journal Article
- Keywords:
corneal biomechanics;
finite element analysis;
vertex displacement;
stress;
radius of curvature
- From:
Journal of Medical Biomechanics
2025;40(3):733-740
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the biomechanical responses after small incision lenticule extraction(SMILE)based on personalized biomechanical parameters of the human eye.Methods Through the results from the correlation analysis between corneal stromal elastic modulus and biomechanical parameters,the cornea elastic modulus was predicted and the material parameters were obtained.Based on clinical measurement data,52 personalized myopic human eye models were reconstructed to analyze the corneal biomechanical response after SMILE.Results The biomechanical response of the cornea varied from patients,and the vertex displacement and stress of the corneal surface increased or decreased after SMILE.On average,when residual stromal thickness(RST)ranged from 278 μm to 332 μm and IOP was 16-20 mmHg(1 mmHg=0.133 kPa),the change of vertex displacement and stress on the corneal surface after SMILE were less than those under IOP=11-16 mmHg.Under RST＞332 μm and IOP=11-16 mmHg,the corneal biomechanics was relatively stable.In addition,the corrected diopters of patients increased,and the deformation of corneal surface after SMILE was more drastic.Conclusions RST and IOP are important factors influencing corneal biomechanics.The material parameters of corneal tissues were predicted based on corneal biomechanical parameters.The cutting profiles and surgical parameters of SMILE may be optimized through analyzing the surgical effect after refractive surgery by reconstructing personalized finite element model of human eyes.
