Effect of hyperbaric oxygen chamber therapy at postoperative early period and its impact on the prognosis of patients with traumatic intracranial hematoma
10.3969/j.issn.1672-8270.2025.06.018
- VernacularTitle:外伤性颅内血肿术后早期实施高压氧舱治疗的效果及对患者预后的影响分析
- Author:
Yanxia YIN
1
;
Lina ZHANG
1
;
Xiuzhen ZHOU
1
Author Information
1. 新疆医科大学第一附属医院神经外三科 乌鲁木齐 830000
- Publication Type:Journal Article
- Keywords:
Traumatic intracranial hematoma;
Hyperbaric oxygen chamber;
Clinically curative effect;
Cerebral hemodynamics;
Marker of brain injury
- From:
China Medical Equipment
2025;22(6):92-96
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate effect of hyperbaric oxygen chamber therapy at postoperative early period and its impact on the prognosis of patients with traumatic intracranial hematoma.Methods:A total of 86 patients with traumatic intracranial hematoma who admitted to the First Affiliated Hospital of Xinjiang Medical University from January 2022 to January 2024 were retrospectively selected,and they were divided into observation group and control group according to random number table,with 43 cases in each group.All patients underwent surgery for treatment,and control group received conventional medicine treatment after surgery,while observation group received hyperbaric oxygen chamber therapy at postoperative early period on the basis of conventional medicine treatment after surgery.The clinically curative effect,cerebral hemodynamics,markers of brain injury,prognostic quality scores,and treatment safety of the two groups were assessed.Results:The total effective rate of the observation group was 93.02%,which was higher than that of the control group(x2=5.460,P<0.05).After treatment,the blood flow velocity(Vd),blood flow volume(BF)and pulsatility index(PI)of cranial arteries of the observation group were higher than those of the control group,and the resistance index(RI)of the observation group was lower than that of the control group(t=5.419,3.459,2.905,4.182,P<0.05).The levels of glial fibrillary acidic protein(GFAP),central nervous system specific protein(S100β)and neuron-specific enolase(NSE)of the observation group were lower than those of the control group after treatment(t=3.865,4.315,5.177,P<0.05).In addition,the scores of national institute of health stroke scale(NIHSS)and modified Rankin scale(mRS)of the observation group were lower than those of the control group,and the score of the comprehensive assessment questionnaire for quality of life(GQOLI-74)of the observation group were higher than those of the control group(t=4.524,5.323,3.676,P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The postoperative early treatment with hyperbaric oxygen chamber for traumatic intracranial hematoma has a favorable effect,which can enhance the cerebral hemodynamics,and reduce the markers'level of brain injury,and improve the prognostic quality of life of patients.Its safety in treatment is favorable.
