Effects of respiratory muscle training combined with phrenic nerve electrical stimulation on coughing abil-ity and lung function in stroke patients with pulmonary infection
10.3969/j.issn.1001-1242.2025.12.011
- VernacularTitle:呼吸肌训练联合膈神经电刺激对脑卒中肺部感染患者咳嗽能力及肺功能的影响
- Author:
Feixiang HUO
1
;
Yalu SUN
1
;
Haidong XU
1
Author Information
1. 济宁医学院附属医院,山东省 济宁市,272000
- Publication Type:Journal Article
- Keywords:
stroke;
lung infection;
respiratory muscle training;
electrical stimulation of phrenic nerve;
cough ability;
lung function
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(12):1838-1843
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of respiratory muscle training(RMT)combined with phrenic nerve electrical stimulation(PNES)on coughing ability and lung function in stroke patients with pulmonary infection.Method:A total of 66 patients with pulmonary infection after stroke,admitted to our hospital from January 2022 to January 2024,were randomly assigned to either an observation group or a control group,with 33 cas-es in each group.During the study,three patients from each group dropped out.Both groups received conven-tional pharmacological and rehabilitation treatment.Additionally,the observation group received combined RMT and PNES,administered once a day,5 days per week,for 4 weeks.Outcome measures included:Cough peak flow rate(CPF),Clinical Pulmonary Infection Score(CPIS),and Borg Dyspnea Scale scores,assessed at baseline,1 week,2 weeks,and 4 weeks.Pulmonary function tests were performed at baseline and after 4 weeks,including maximum inspiratory pressure(MIP),maximum expiratory pressure(MEP),forced vital ca-pacity(FVC),forced expiratory volume in the first second(FEV1),maximum volume per minute(MVV).The percentages of predicted values(FVC％,FEV1％,MVV％)were calculated.Coughing ability and pulmo-nary function were compared between the groups.Result:At baseline and after 1 week of treatment,there were no significant between-group differences in CPF,CPIS,or Borg Dyspnea scores(P>0.05).However,after 2 and 4 weeks of treatment,the observation group showed significantly greater improvements in CPF,CPIS,and Borg Dyspnea scores compared to the control group(P<0.05).Furthermore,after 4 weeks of treatment,the improvement in all pulmonary function parame-ters(MIP,MEP,FVC％,FEV1％,MVV％)was significantly greater in the observation group than in the con-trol group(P<0.05).Conclusion:Respiratory muscle training combined with phrenic nerve electrical stimulation can effectively improve the coughing ability,alleviate pulmonary infection,and enhance lung function in stroke patients within a short peri-od of time,which is worthy of promotion and application in the treatment of lung infection in early stroke.
