Analysis of the current status of hospital-acquired infections in cancer patients based on disease diagnosis-related groups
10.11816/cn.ni.2025-248702
- VernacularTitle:基于疾病诊断相关分组的肿瘤患者医院感染现状分析
- Author:
Xu HAN
1
;
Xiaoqin ZHANG
1
;
Xiaoqin CAO
1
;
Tiantian ZHAO
1
;
Xia ZHAO
1
Author Information
1. 郑州大学附属肿瘤医院(河南省肿瘤医院)感控管理办公室,河南郑州 450008
- Publication Type:Journal Article
- Keywords:
Diagnosis-related groups;
Cancer patients;
Hospital-acquired infection;
Current status;
Case mix index
- From:
Chinese Journal of Nosocomiology
2025;35(11):1702-1706
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the current status of hospital-acquired infections(HAI)in cancer patients in Henan Cancer Hospital,and explore the application of Case Mix Index(CMI)based on disease diagnosis-related groups(DRG)in the evaluation of HAI risks.METHOD Data on HAI of patients in cancer hospitals in Henan Province from Jun.2023 to Jun.2024 were statistically analyzed,including incidence rates,distribution of infec-tion sites and composition ratios of pathogens,high-risk departments were identified by CMI-adjusted 1 000-day incidence rates of HAI infections,and the current status of HAI in cancer patients were analyzed.RESULTS The incidence of HAI in cancer patients was 1.67％(4 315/259 087),and the incidence rate of HAI in 1 000 days was 2.46 per 1000.The sites of infection were mainly the respiratory tract,the abdominal cavity,the surgical sites and the bloodstream.A total of 2 381 strains of pathogens were cultured and isolated,including 1 570 strains of gram-negative bacteria,638 strains of gram-positive bacteria and 173 strain s of fungi,and the top five strains de-tected were Escherichia coli(24.49％),Klebsiella pneumoniae(15.41％),Pseudomonas aeruginosa(9.11％),Staphylococcus aureus(8.86％)and Staphylococcus epidermidis(4.66％).After CMI adjustment,the order of decreasing was dominated by surgical departments,while the order of increasing was dominated by non-surgical departments,and the top five departments with the highest adjusted incidence rates were Orthopedics and Soft Tissue department,Hematology department,Hepatobiliary Surgery department,General Surgery department and Urology department.CONCLUSIONS In the prevention and control of HAI in cancer patients,attention should be given to the gram-negative bacteria,and close monitoring of infections in the respiratory tract,abdominal cavity,and surgical sites is essential.This study uses the CMI to adjust the HAI incidence rate of cancer patients in order to identify high-risk departments that currently require focused management,it also analyzes the DRGs codes with a highest proportion of HAI in each department,with a particular focus on patients in these high-risk groups,and it aims to avoid and minimize the occurrence of HAI among cancer patients as much as possible through refined DRGs analysis and targeted prevention and control measures.
