Practice and efficacy of refined management on antimicrobial agents in chest specialty hospital
10.12138/j.issn.1671-9638.20252747
- VernacularTitle:胸科专科医院抗菌药物精细化管理实践与成效分析
- Author:
Na ZHU
1
;
Ye LI
;
Haihua DING
;
Yan YANG
;
Rui JIANG
;
Shuya XUE
;
Xinli WU
;
Yunling ZHANG
Author Information
1. 安徽省胸科医院药剂科,安徽 合肥 230022
- Publication Type:Journal Article
- Keywords:
antimicrobial agent;
rational antimicrobial use;
scientific management;
grid-based management of clinical pharmacists;
chest hospital
- From:
Chinese Journal of Infection Control
2025;24(11):1634-1640
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application efficacy of refined management on antimicrobial agents in a chest specialty hospital.Methods Multiple measures were implemented through perfecting management systems and processes,as well as conducting knowledge training,such as multi-dimensional specialized prescription reviewing,optimizing information systems,and implementing grid-based management of clinical pharmacist.A refined manage-ment mode for antimicrobial agents in a chest specialty hospital has been established.Antimicrobial management in-dicators for the whole hospital and each clinical specialty in 2023(before management)and 2024(after manage-ment)were analyzed.Results Compared with 2023,antimicrobial use rate among hospitalized patients in 2024 de-creased from 47.48%to 45.92%,and antimicrobial use density(AUD)decreased from 46.28 defined daily doses(DDDs)/(100 person·day)to 39.73 DDDs/(100 person·day).The ratio of antimicrobial cost to total drug cost decreased from 12.71%to 9.51%,and the per capita cost of antimicrobial use decreased from 1 344.18 Yuan to 975.52 Yuan.The use rate of prophylactic antimicrobial agents for class Ⅰ incision surgery increased from 84.48%to 89.52%,and the rationality rate increased from 69.25%to 94.53%.The management indicators of each clinical specialty improved significantly.Conclusion Through adopting a series of refined management measures,antimi-crobial management modes that are suitable for the actual situation of the hospital has been constructed,and obvious efficacy was achieved.Clinical application of antimicrobial agents is more standardized and rational.