The NO-sGC-cGMP pathway and heart failure
- VernacularTitle:NO-sGC-cGMP通路在心力衰竭中的研究进展
- Author:
Dilu LI
1
;
Yuanyuan PEI
1
;
Wuchao WANG
1
;
Lingjie CAO
1
;
Fengtao YANG
1
;
Shuangkui SHI
1
;
Guyue ZHOU
1
;
Kunyu YANG
1
;
Jihong ZHU
1
Author Information
- Publication Type:Journal Article
- Keywords: heart failure; signaling pathway; ni-tric oxide; soluble guanylate cyclase; cyclophos-phate guanylate
- From: Chinese Journal of Clinical Pharmacology and Therapeutics 2025;30(5):702-708
- CountryChina
- Language:Chinese
- Abstract: Heart failure,as a global public health challenge,is experiencing an increasingly severe disease burden.Given the close relationship be-tween the Nitric Oxide-Soluble Guanylate Cyclase-Cyclic Guanosine Monophosphate(NO-sGC-cGMP)signaling pathway and heart failure,this study,through a comprehensive search and review of re-cent literature on the NO-sGC-cGMP pathway and heart failure,aims to outline the mechanism of ac-tion of this signaling pathway and its connection with heart failure,in order to explore new avenues for the treatment of heart failure.
