Analysis and theoretical discussion on prescriptions for the treatment of Sj?gren syndrome with traditional Chinese medicine
10.3969/j.issn.1673-9701.2025.16.017
- VernacularTitle:中医药治疗干燥综合征的方药分析及理论探讨
- Author:
Xixi LIU
1
;
Zeguang LI
;
Tiantian QIU
;
Xue WANG
;
Fanying MENG
Author Information
1. 北京市门头沟区中医医院针灸科,北京 102300
- Publication Type:Journal Article
- Keywords:
Sj?gren syndrome;
Dryness-related impediment;
Data mining;
Medication rule;
Theoretical discussion
- From:
China Modern Doctor
2025;63(16):74-77,84
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the core theories and medication characteristics of traditional Chinese medicine in the treatment of Sj?gren syndrome(SS).Methods Search for relevant literatures on the treatment of SS with traditional Chinese medicine published in CNKI,Wanfang Data Knowledge Service Platform,VIP,and SinoMed from the establishment of the database to September 30,2022,screen the prescriptions for the treatment of SS with traditional Chinese medicine and conduct data mining.Results A total of 137 prescriptions were finally selected,involving 186 Chinese medicines.Among them,yin-nourishing medicines,interior heat-clearing medicines and qi-tonifying medicines were used most frequently,and Maidong,Shengdihuang,Baishao ranked among the top 3 in terms of usage frequency.The four qi of Chinese medicines were mainly based on the cold,and the five flavors were based on the sweet flavors.The channel tropism were based on lung meridian and liver meridian.Entropy clustering analysis finally obtained four new prescriptions.Conclusion The treatment of SS is based on nourishing yin for moistening dryness,invigorating spleen and replenishing qi,removing toxicity substance and resolving macula,and dredging channels.At the same time,it emphasizes the application of concepts such as sour and sweet transform into yin,body fluids and blood share the same source,and seeking yin from yang.