Optimization of radiation source arrangement in brachytherapy for linear keloids
10.3969/j.issn.1005-202X.2025.11.003
- VernacularTitle:线形瘢痕疙瘩术后放疗中放射源排布的优化
- Author:
Siyu XIN
1
;
Liangang GE
;
Qiuchi CHEN
;
Jizeng MENG
;
Jian ZHANG
;
Fulin GAO
Author Information
1. 吉林市第二人民医院放射治疗科,吉林吉林 132000
- Publication Type:Journal Article
- Keywords:
keloid;
brachytherapy;
dose optimization;
source-to-skin distance;
source spacing
- From:
Chinese Journal of Medical Physics
2025;42(11):1414-1419
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the dose distribution of postoperative brachytherapy for linear keloids,and to investigate the effects of the number of radiation sources n,source-to-skin distance d,and source spacing a on dose distribution,thereby providing a reasonable radiation source arrangement scheme for radiotherapy in narrow and elongated wound areas.Methods A one-dimensional idealized model was established.Based on the inverse-square law,dose distributions were calculated under combinations of differentn(4,6,8,10)and d(from 0.3 to 2.0 cm).The proportions of dose-effective areas(90%-110%of the prescribed dose)and penumbra areas(20%-80%of the prescribed dose)were analyzed to evaluate the rationality of dose distribution.Results When d/a slightly exceeded 0.5,the proportion of the effective area reached its peak,and the proportion of the penumbra area was relatively low.An excessively small d/a led to cold spots in the irradiated area,while an excessively large d/a expanded the penumbra area.Increasing n significantly reduced the penumbra range and improved dose homogeneity.Conclusion The dose distribution is most reasonable when d/a is slightly greater than 0.5,and a multi-source arrangement(n≥6)is preferred to enhance dose homogeneity.This study provides guidance for parameter optimization in brachytherapy for keloids.
