Research progresses of novel PET imaging probes nanobodies
10.13929/j.issn.1003-3289.2025.05.030
- VernacularTitle:新型PET显像探针纳米抗体研究进展
- Author:
Meng WANG
1
;
Li CHEN
;
Penghui SUN
;
Yanjiang HAN
Author Information
1. 南方医科大学南方医院核医学科,广东 广州 510515;广东省药品监督管理局放射性药物质量控制与评价重点实验室,广东 广州 510515
- Publication Type:Journal Article
- Keywords:
nanoparticles;
molecular probes;
positron-emission tomography
- From:
Chinese Journal of Medical Imaging Technology
2025;41(5):835-838
- CountryChina
- Language:Chinese
-
Abstract:
Nanobodies(Nb)have become novel probes for PET imaging instead of traditional antibodies,which have broad application prospects due to advantages of small molecular weight,strong stability and permeability,passing through the blood-brain barrier and low immunogenicity.The research progresses of structural characteristics of Nb,labeling methods of positron isotopes and application of labeled products in PET imaging were reviewed in this article.
