Current status of distribution of hospitalized patients with latent tuberculosis infection and comorbidities in a tertiary general hospital
10.11816/cn.ni.2025-250202
- VernacularTitle:某三级综合医院住院患者结核潜伏感染共病分布现状
- Author:
Jingyu XING
1
;
Lingfeng WANG
;
Lurong JIA
;
Mengmeng HAO
;
Mingyan LIU
;
Yan JIANG
;
Liping GUO
Author Information
1. 北京中医药大学管理学院,北京 100029;中日友好医院医院感染管理办公室,北京 100029
- Publication Type:Journal Article
- Keywords:
Latent tuberculosis infection;
Hospital-associated infection;
Comorbidity;
Standardized management
- From:
Chinese Journal of Nosocomiology
2025;35(10):1489-1495
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the diagnosis of latent tuberculosis infection(LTBI)in hospitalized patients of a tertiary general hospital and investigate the current status of related comorbidities.METHODS The clinical data were collected from the 14 448 hospitalized patients who received tuberculin skin test(TST)or interferon-gamma release assay(IGRA)in China-Japan Friendship Hospital from Jan.1,2022 to Dec.31,2023,and the results were assessed.RESULTS The detection rate of LTBI was 23.62％(3413/14448)among the hospitalized patients who received the tests,and the rate of definite diagnosis was only 4.22％(144/3413).88.40％(3017/3413)of the hospitalized patients with LTBI had at least one type of comorbidity,and the top 5 comorbidities were in turn as follows:high blood pressure,hyperlipidemia,diabetes mellitus,malignant tumors and rheumatic immune disea-ses;the number of comorbidities was increased with the age(x2=291.199,P＜0.001).The rheumatic immune disease(73/144,50.69％)was the most common type of comorbidity among the hospitalized patients with definite diagnosis of LTBI,and less than half of the patients(66/144,45.83％)were treated in rheumatology and immu-nology department.CONCLUSION The two-way screening of LTBI and comorbidities is the core premise for the standardized management of LTBI.
