Time-to-event analysis in evaluating the efficacy of drugs against multidrug-resistant gram-negative bacterial infections
10.12092/j.issn.1009-2501.2025.07.015
- VernacularTitle:时间-事件分析在评价抗多重耐药革兰阴性菌感染药物疗效中的应用
- Author:
Qin DING
1
;
Ruwei YANG
;
Shengnan ZHANG
;
Guoping YANG
;
Qi PEI
Author Information
1. 中南大学湘雅三医院药学部
- Publication Type:Journal Article
- Keywords:
multidrug-resistant gram-negative bacteria;
time-to-event analysis;
mortality;
clinical prognosis
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(7):998-1008
- CountryChina
- Language:Chinese
-
Abstract:
The treatment of multidrug-resistant gram-negative bacterial infections has become a challenge in today's healthcare field,and time-to-event data analysis has shown significant value in clinical prognostic studies of critically ill patients.This study comprehensively reviewed the results of the application of time-to-event analysis in clinical studies of anti-multidrug-resistant gram-negative bacterial drugs,aiming to provide a scientific basis for the optimization of therapeutic strategies and prognostic assessment of multidrug-resistant gram-negative bacterial infections,and to promote the widespread application of time-to-event analysis methods in similar studies.