Research progress on the clinical application and mechanism of com-monly used traditional Chinese medicine in the treatment of breast cancer
10.12092/j.issn.1009-2501.2025.07.013
- VernacularTitle:常用中成药治疗乳腺癌的临床应用及作用机制研究进展
- Author:
Shanshan LI
1
;
Dandan WEI
;
Hanyu KANG
;
Xiaopeng LIU
;
Shuxun YAN
;
Shiqing JIANG
Author Information
1. 河南中医药大学第一附属医院内分泌科,郑州 450000,河南;河南中医药大学第一临床医学院,郑州 450000,河南
- Publication Type:Journal Article
- Keywords:
breast cancer;
Chinese patent medi-cine;
mechanism of action;
clinical application
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(7):977-983
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is a common clinical gy-necological tumor.According to the 2022 global cancer data statistics,breast cancer ranks second in terms of incidence among newly diagnosed cancer cases worldwide.Modern medicine often adopts surgical operation,chemotherapy,and other meth-ods,which have certain efficacy but also many problems such as high drug resistance rates and sig-nificant adverse reactions.Chinese patent medi-cines exhibit extensive anticancer effects.The study found that Shenyi Capsule,Pingxiao Capsule,and Zhenqi Fuzheng Granules were widely used in the treatment of breast cancer,exerting therapeu-tic effects on breast cancer by inhibiting cell prolif-eration,invasion,and metastasis,suppressing an-giogenesis,reversing cellular drug resistance,and inhibiting precancerous lesions.Meanwhile,the oral administration of Chinese patent medicines in combination with other traditional Chinese medi-cine(TCM)compounds,TCM decoctions,or mod-ern medical treatments can improve patients' quali-ty of life and reduce adverse reactions.Currently,there are numerous studies on the treatment of breast cancer with Chinese patent medicines,but a systematic summary is lacking.Therefore,this study conducted a systematic review of the mecha-nisms of action and clinical applications of Chinese patent medicines as adjuvant therapy for breast cancer,aiming to provide guidance for clinical medi-cation.
