Methodological Problems and Solutions Commonly Encountered in Scientific Reviews of Investor Initiated Trial in the Field of Traditional Chinese Medicine
- VernacularTitle:中医药领域研究者发起的临床研究科学性审查中常见的方法学问题及解决策略
- Author:
Fang HAN
1
;
Jia XU
;
Baoli LIU
;
Qingquan LIU
;
Bin LI
;
Jing HU
Author Information
- Publication Type:Journal Article
- Keywords: TCM; Investor initiated trial; Scientific review; Methodology
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(6):1509-1513
- CountryChina
- Language:Chinese
- Abstract: The number of investor initiated trial(IIT)in the field of traditional Chinese medicine(TCM)in China has been increasing year by year,but there are still many problems about their scientific validity.Scientific review is the top priority of IIT management,which is of great significance to improve the quality of IIT.Considering the characteristics of IIT in the field of TCM,randomized controlled trials and discuss common methodological problems in the scientific review process of IIT are focused on,such as non-standard placebo setting,unclear research hypothesis or improper selection of hypothesis test type,inappropriate sample size estimation methods,insufficient characteristics of TCM in outcome measures,unreasonable statistical analysis methods,etc.At the same time,corresponding solutions are proposed to increase the scientific and credibility of IIT,thus improving the research quality of IIT in TCM.
