Research progress of necroptosis in chronic airway inflammatory diseases
10.3969/j.issn.1672-8467.2025.06.015
- VernacularTitle:坏死性凋亡在慢性气道炎症性疾病中的研究进展
- Author:
Weng-lam CHOI
1
;
Yue-ren WU
;
Jing SUN
;
Zhen GAO
;
Jing-cheng DONG
Author Information
1. 复旦大学附属华山医院中西医结合科 上海 200040
- Publication Type:Journal Article
- Keywords:
necroptosis;
chronic airway inflammatory diseases;
pathogenesis
- From:
Fudan University Journal of Medical Sciences
2025;52(6):892-896,916
- CountryChina
- Language:Chinese
-
Abstract:
The mode of cell death as well as the role of necroptosis in inflammatory diseases has gained importance in recent years.Chronic airway inflammatory diseases are common respiratory diseases,such as chronic obstructive pulmonary disease(COPD)and asthma,which are often accompanied by persistent airway inflammation,and the pathogenesis of these diseases is complex and involves cell death pathways.The involvement of necroptosis in their pathogenesis is getting more and more attention.This review introduces reviewed the important pathways and factors of necroptosis,as well as its advances in mechanism of chronic airway inflammatory diseases,aiming to provide new ideas and targets for the research and treatment of chronic airway inflammatory diseases.
