Clinical observation of Endo-LOVE combined with NR-PRF in the treatment of LDD:Focusing on the im-provement of postoperative residual symptoms
10.3969/j.issn.1006-5725.2025.12.005
- VernacularTitle:Endo-LOVE联合内镜下神经根射频脉冲治疗腰椎退行性疾病临床疗效
- Author:
Rouzi REBOTE
1
;
Hanshuo ZHANG
;
Guangnan YANG
;
Jie BAI
;
Qiang JIANG
;
Zhengcao LU
;
Wen LI
;
Yu DING
Author Information
1. 解放军医学院(北京 100853);解放军总医院第六医学中心中医医学部骨伤科(北京 100048)
- Publication Type:Journal Article
- Keywords:
lumbar degenerative disease;
endoscopic decompression;
nerve root pulsed radiofre-quency;
combination therapy;
clinical efficacy
- From:
The Journal of Practical Medicine
2025;41(12):1800-1807
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effectiveness of full endoscopic lamina fenestration discec-tomy(Endo-LOVE)in combination with nerve root pulsed radiofrequency(NR-PRF)in the treatment of lumbar degenerative disease(LDD),along with the amelioration of postoperative residual symptoms.Methods A retro-spective analysis was performed on 102 patients with LDD who were treated in our hospital between January 2022 and June 2023.Among them,53 cases were assigned to the observation group(receiving Endo-LOVE combined with NR-PRF),and 49 cases were included in the control group(undergoing Endo-LOVE alone).The mean follow-up period was 15.05±1.15 months.The general data of the two groups were compared.Observations were carried out at preoperative,1-day,7-day,1-month,3-month,6-month,and final follow-up time points postopera-tively.The perioperative data and follow-up outcomes of the two groups were compared.Results Prior to surgery,no significant disparities were detected in the general conditions and clinical observation indicators(VAS,M-JOA,and ODI scores)between the two groups.Postoperatively,both groups exhibited a notable improvement in clinical indicators when compared to the preoperative levels(P<0.05).Within three months after surgery,the observation group showed significantly more pronounced improvement in all clinical indicators than the control group(P<0.05).At six months postoperatively and during the final follow-up,no statistically significant differences in clinical indi-cators were found between the two groups.Moreover,at the final follow-up,there was no statistically significant difference in the Macnab scores between the two groups(P>0.05).Conclusion Endoscopic decompression for the treatment of LDD exhibits high safety and reliability.When combined with endoscopic NR-PRF,it enhances the clinical efficacy,reduces the incidence of postoperative residual symptoms,and facilitates rapid postoperative recovery.This complementary combination presents a novel therapeutic strategy for LDD.
