Research progress of CAR-T cell therapy in bladder cancer
- VernacularTitle:嵌合抗原受体T细胞疗法在膀胱癌中的研究进展
- Author:
Zongjian HU
1
;
Shun WAN
1
;
Jianwei YANG
1
;
Li WANG
1
;
Siyu CHEN
1
;
Li YANG
1
Author Information
- Publication Type:Journal Article
- Keywords: chimeric antigen receptor T cell; bladder cancer; immunotherapy
- From: The Journal of Practical Medicine 2025;41(22):3496-3500
- CountryChina
- Language:Chinese
- Abstract: Bladder cancer(BCa)is a common malignant tumor of the urinary system,and its conventional treatment methods have many limitations.Chimeric antigen receptor T cell(CAR-T)therapy,as an emerging immunotherapy method,has achieved significant success in hematological malignancies and has brought new hope for the treatment of solid tumors.This article reviews the research progress of CAR-T cell therapy in the treatment of BCa,including the basic structure of CAR-T cells,potential therapeutic targets in bladder cancer,current chal-lenges and corresponding strategies.
