Pathogenesis, risk factors and treatment of low anterior resection syndrome after colon surgery
10.3760/cma.j.cn441530-20250317-00105
- VernacularTitle:结肠术后低位前切除综合征的发病机制和影响因素及治疗进展
- Author:
Yuchen GUO
1
;
Hanxiao ZHAO
1
;
Quan WANG
1
Author Information
1. 吉林大学第一医院普通外科中心 胃结直肠外科，长春 130021
- Publication Type:Journal Article
- Keywords:
Low anterior resection syndrome;
Surgery, colectomy;
Defecation dysfunction
- From:
Chinese Journal of Gastrointestinal Surgery
2025;28(6):633-638
- CountryChina
- Language:Chinese
-
Abstract:
Low anterior resection syndrome (LARS) is a series of symptoms of intestinal dysfunction, and its research is mainly focused on patients with low rectal surgery. However, with the deepening understanding of postoperative LARS, surgeons found that LARS not only exists among patients who have undergone low anterior resection of rectum, but also plagues a considerable number of patients who have undergone non-rectal (mainly colon) surgeries. This article aims to elaborate on the incidence and treatment of LARS after colon surgery. Through a comprehensive analysis of relevant studies, it is found that the incidence of LARS after colon surgery is approximately 20%-30%, and the incidence is relatively higher in patients undergoing right hemicolectomy. Its pathogenesis is related to multiple factors, including surgical methods, resection range, changes in intestinal flora, patient age, gender, and underlying diseases. Treatment methods include conservative treatments such as dietary adjustment, drug therapy, transanal irrigation, and rehabilitation training. Single treatment methods have limited effect, while comprehensive treatment can effectively improve patients' symptoms and quality of life. The current LARS scoring system has not been effectively verified in the application after colon cancer surgery, and it is necessary to develop a more targeted scoring system.
