Correlation between triglyceride-glucose index and hypertension in patients with cerebral hemorrhage

Jiawen DONG; Xin ZOU; Hui TANG; Ting LIU; Shiwen ZHANG; Ye WANG; Shaojing SHI; Jinsheng ZHANG; Jing LI

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Correlation between triglyceride-glucose index and hypertension in patients with cerebral hemorrhage

VernacularTitle:脑出血患者三酰甘油-葡萄糖指数与高血压的相关性研究
Author: Jiawen DONG ¹ ; Xin ZOU ¹ ; Hui TANG ¹ ; Ting LIU ¹ ; Shiwen ZHANG ¹ ; Ye WANG ¹ ; Shaojing SHI ¹ ; Jinsheng ZHANG ¹ ; Jing LI ¹
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1. 300381 天津中医药大学第一附属医院针灸科国家中医针灸临床医学研究中心
Publication Type:Journal Article
Keywords: cerebral hemorrhage; hypertension; correlation of data; regression analysis
From: Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2025;27(3):303-307
CountryChina
Language:Chinese
Abstract: Objective To explore the relationship between triglyceride-glucose(TyG)index and hypertension in patients with cerebral hemorrhage.Methods A total of 1718 patients with cere-bral hemorrhage admitted to our hospital from January,2013 to May,2023 were enrolled in this study.According to the TyG index quartile,437 cases were assigned into Q1 group(≤8.375),424 cases into Q2 group(TyG index 8.376～8.737),429 cases into Q3 group(TyG index 8.738～9.087),and 428 cases into Q4 group(≥9.088).The general clinical data were compared in the four groups.Logistic regression analysis was used to study the correlation between TyG index and hy-pertension.Results There were significant differences among the four groups in terms of age,hy-pertension,diabetes,SBP,DBP,TC,TG,HDL-C,LDL-C,FBG,glycated hemoglobin and TyG in-dex(P＜0.05,P＜0.01).Logistic regression analysis showed that when the TyG index was a con-tinuous variable,it was significantly correlated with the risk of hypertension(OR=1.999,95％CI:1.393-2.869,P=0.001).When the index was used as a categorical variable,with Q1as a ref-erence,TyG index in Q3 and Q4 was associated with an increase in OR of hypertension(OR=1.869,95％CI:1.220-2.865,P=0.004;OR=1.844,95％CI:1.125-3.020,P=0.015).After ad-justing cofounders,the association of TyG index and risk of hypertension was stronger in the fe-males(OR=2.618,95％CI:1.312-5.221,P=0.006)than the males(OR=1.783,95％CI:1.151-2.761,P=0.010),and in the patients ≥65 years old(OR=3.277,95％CI:1.600-6.741,P=0.001)than those＜65 years old(OR=1.782,95％CI:1.076-2.949,P=0.025).Conclusion TyG index is closely associated with hypertension in patients with cerebral hemorrhage,especially in women and elderly.