Status and influencing factors of frailty in elderly people participating in health check-up in outpatient clinic
10.3969/j.issn.1009-0126.2025.03.003
- VernacularTitle:门诊老年健康体检者衰弱状况及影响因素分析
- Author:
Wenkai XIAO
1
;
Xiaona WANG
1
;
Jin ZHENG
1
;
Xiangzhu XIE
1
;
Li SHENG
1
Author Information
1. 100853 北京,解放军总医院第二医学中心心血管内科 国家老年疾病临床医学研究中心
- Publication Type:Journal Article
- Keywords:
frailty;
multiple chronic conditions;
risk factors;
aged
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(3):265-269
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of frailty among the health check-up elder-ly participants from our outpatient clinic.Methods A total of 710 elderly individuals(≥60 years old)who taking health check-up in our outpatient department between April and August 2022 were consecutively enrolled,and according to the results of Fried Frailty Phenotype Scale,they were divided into non-frailty group(422 cases),pre-frailty group(225 cases)and frailty group(63 cases).Their general clinical data,laboratory indicators and echocardiographic parameters were collected,and multivariate logistic regression analysis was applied to identify the independent in-fluencing factors for pre-frailty and frailty.Results The overall prevalence of pre-frailty and frail-ty was 31.7％and 8.9％,respectively.The pre-frailty and frailty groups had obviously larger left atrial anterior-posterior diameter and left ventricular end diastolic diameter and lower left ventric-ular ejection fraction when compared with the non-frailty group(P＜0.05).Multivariate logistic regression analysis showed that Hb was a protective factor for pre-frailty in the elderly partici-pants(OR=0.984,95％CI:0.966-0.992,P=0.048),while age(OR=1.064),CCI(OR=1.387)and LAAP(OR=1.059)were risk factors for pre-frailty in them(P＜0.05,P＜0.01).Serum albumin was a protective factor for frailty(OR=0.823,95％CI:0.728-0.931,P=0.002),but age(OR=1.081),CCI(OR=1.458),left atrial anterior-posterior diameter(OR=1.249)and NT-proBNP(OR=1.652)were independent risk factors for frailty(P＜0.05,P＜0.01).Conclusion There are differences in influencing factors for frailty of different severity,and the status of frailty is related to factors such as age,comorbidity,cardiac function and nutritional sta-tus.Therefore,comprehensive interventions should be implemented as early as possible for the elderly occurrence of pre-frailty so as to prevent and reverse frailty at the same time.
