Chemical constituents from salt-processed Litchi Semen and their antioxidant activities
10.3969/j.issn.1001-1528.2025.02.019
- VernacularTitle:盐炙荔枝核化学成分及其抗氧化活性研究
- Author:
Rui YIN
1
;
Xing YANG
1
;
Wei-mao DONG
1
;
Xu-li DENG
1
;
Yi-mou WANG
1
;
Hong-chuan ZHANG
1
;
Kui-lin ZHU
1
;
Zhang-xian CHEN
1
;
Hong-ping HE
1
;
Fa-wu DONG
1
Author Information
1. 云南中医药大学中药学院,云南省南药可持续利用研究重点实验室,云南 昆明 650500
- Publication Type:Journal Article
- Keywords:
salt-processed Litchi Semen;
chemical constituents;
isolation and identification;
antioxidant activities;
DPPH free radical;
ABTS+free radical
- From:
Chinese Traditional Patent Medicine
2025;47(2):480-486
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from salt-processed Litchi Semen and their antioxidant activities.METHODS The 85％ethanol extract from salt-processed Litchi Semen was isolated and purified by silica gel,Sephadex LH-20,MCI,ODS and semi-preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.DPPH and ABTS+free radical scavenging method were used to evaluate their antioxidant activities.RESULTS Fifteen compounds were isolated and identified as dehydrocostuslactone(1),ananosmoside A(2),funingensin A(3),(2S)-pinocembrin-7-O-(6-O-α-L-rhamnopyranosyl-β-D-glucopyranoside)(4),liquiritienin(5),quercetin(6),rutin(7),isorhamnetin-3-O-β-rutinoside(8),procyanidin A2(9),procyanidin A1(10),ethyl protocatechuate(11),5-hydroxymethylfurfural(12),di(2-ethyl-hexyl)phthalate(13),nicotinamide(14),(10E,15Z)-9,12,13-trihydroxyoctadeca-10,15-dienoic acid(15).Compounds 6-7,9-10 exhibited scavenging activities against DPPH radicals with IC50 values of(12.929±1.232),(14.104±0.946),(10.417±1.736),(6.944±0.030)μmol/L,respectively.Compounds 6-10 exhibited scavenging activities against ABTS+radicals with IC50 values of(21.952±0.577),(25.683±0.625),(22.970±1.336),(20.210±1.435),(18.725±0.324)μmol/L,respectively.CONCLUSION Compounds 1,5,14-15 are isolated from Litchi genus for the first time.Compounds 6-7,9-10 have strong in vitro antioxidant activities.
