Changes and significance of coagulation function indicators in elderly patients with severe pneumonia
10.3969/j.issn.1673-9701.2025.04.009
- VernacularTitle:老年重症肺炎患者凝血功能指标变化及意义
- Author:
Yingchao LIU
1
;
Lina ZHANG
;
Qiuyue ZHANG
;
Zhen LI
;
Jia TIAN
Author Information
1. 聊城市第二人民医院检验科,山东临清 252600
- Publication Type:Journal Article
- Keywords:
Severe pneumonia;
Coagulation function;
Fibrinogen;
D-dimer;
Platelet
- From:
China Modern Doctor
2025;63(4):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of changes in coagulation function related indexes in elderly patients with severe pneumonia.Methods A total of 127 elderly patients with severe pneumonia admitted to the Second People's Hospital of Liaocheng from January 2022 to December 2023 were included in observation group,and 135 patients with common pneumonia admitted during the same period were included in control group.The indexes of coagulation function[platelet(PLT),prothrombin time(PT),fibrinogen(FIB),activated partial thromboplastin time(APTT),thrombin time(TT),D-dimer(D-D)]within 24h after admission were compared between two groups.Results The age of patients in observation group was significantly higher than that in control group,and the proportion of smoking history,underlying disease and underlying disease≥2 was significantly higher than that in control group(P＜0.05).The positive rates of PT and D-D in observation group were significantly higher than those in control group(P＜0.05).PT and TT in observation group were significantly longer than control group,D-D level was significantly higher than that in control group,PLT level was significantly lower than that in control group(P＜0.05).Conclusion Patients with severe pneumonia often have abnormal coagulation function,and the detection of related indexes of coagulation function is of great significance to evaluate the condition of patients.
