Construction of a Clinical Early Warning Model for Bladder Spasm Occurred after TURP in Patients with Benign Prostatic Hyperplasia Based on LASSO Regression
10.13241/j.cnki.pmb.2025.19.008
- VernacularTitle:基于LASSO回归构建良性前列腺增生患者TURP术后膀胱痉挛发生的临床预警模型
- Author:
Hong-jin WANG
1
;
Xiao-yun WU
1
;
Yun-fang LIU
1
;
Qing-na CUI
1
Author Information
1. 黄河三门峡医院泌尿外科 河南三门峡 472000
- Publication Type:Journal Article
- Keywords:
Benign prostatic hyperplasia;
Transurethral resection of the prostate;
Bladder spasm;
LASSO regression;
Early warning model
- From:
Progress in Modern Biomedicine
2025;25(19):3091-3097
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To construct a clinical early warning model for bladder spasm occurred after transurethral resection of the prostate(TURP)in patients with benign prostatic hyperplasia(BPH)based on LASSO regression.Methods:The clinical data of 139 patients with BPH who underwent TURP treatment in Yellow River Sanmenxia Hospital from January 2022 to June 2024 were prospectively selected,and they were divided into spasm group(39 cases)and non-spasm group(100 cases)according to whether bladder spasm occurred after surgery.The characteristics of bladder spasm occurred after TURP in patients with BPH were statistically analyzed,and the general data between the two groups were compared.LASSO regression was used to screen the characteristic variables related to bladder spasm occurred after TURP,multivariate logistic regression was used to analyze the influencing factors of bladder spasm after TURP.The prediction model of bladder spasm after TURP was constructed,and the receiver operating characteristic(ROC)curve was drawn to evaluate the efficacy of the prediction model.Results:The incidence of bladder spasm after TURP was 28.06％.There were significant differences in age,history of diabetes,operation time,temperature of irrigating fluid,traction tension of urinary catheter,prostate volume and postoperative hospital stay between non-spasm group and spasm group(P＜0.05).LASSO regression showed that operation time,age,traction tension of urinary catheter,temperature of irrigating fluid,history of diabetes were important characteristics of bladder spasm occurred after TURP.Multivariate logistic regression analysis showed that old age,history of diabetes and long operation time were independent risk factors of bladder spasm occurred after TURP(P＜0.05).ROC curve showed that the area under the curve(AUC)of the risk prediction model for bladder spasm occurred after TURP was 0.885(95％CI:0.752-0.921).Conclusions:Old age,history of diabetes and long operation time are independent risk factors of bladder spasm occurred after TURP,the clinical warning model based on LASSO regression has a certain value in predicting the risk for bladder spasm occurred after TURP,which helps to identify high-risk patients early.
