Application progress in Mendelian randomization on migraine
10.3969/j.issn.1004-1648.2025.03.011
- VernacularTitle:孟德尔随机化在偏头痛研究中的应用进展
- Author:
Yalu MENG
1
;
Shaokang WANG
1
;
Tianlong YIN
1
Author Information
1. 300000 天津中医药大学第一附属医院针灸部·国家中医针灸临床医学研究中心
- Publication Type:Journal Article
- Keywords:
Mendelian randomization;
migraine;
risk factors;
genome-wide association studies
- From:
Journal of Clinical Neurology
2025;38(3):212-216
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,Mendelian randomization based on Genome-wide association study has been widely applied to explore the etiology of various diseases.The method utilizes genetic variants strongly associated with risk factors as instrumental variables to investigate the causal relationship between exposure factors and outcome indicators.This paper reviews the progress of Mendelian randomization in the study of migraine,aiming to provide reference for the research on the mechanisms,diagnosis,treatment,and prevention of migraine.