Study on the Relationship between Mechanical Ventilation Based on Volumetric Guaranteed Ventilation Mode and Weaning Outcomes of Neonatal Respiratory Distress Syndrome
10.13241/j.cnki.pmb.2025.19.013
- VernacularTitle:基于容量保证通气模式下的机械通气与新生儿呼吸窘迫综合征撤机结局的关系研究
- Author:
Hai-yan WANG
1
;
Li-li YAN
1
;
Hai-xia WU
1
;
Ying-ying CHEN
1
;
Wen-yan TANG
1
Author Information
1. 江西省妇幼保健院新生儿科 江西南昌 330038
- Publication Type:Journal Article
- Keywords:
Pressure-controlled ventilation;
Volumetric guaranteed;
Mechanical ventilation;
Neonatal;
Respiratory distress syndrome;
Weaning outcomes
- From:
Progress in Modern Biomedicine
2025;25(19):3131-3138
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between mechanical ventilation based on volumetric guaranteed(VG)ventilation mode and weaning outcomes of neonatal respiratory distress syndrome(RDS).Methods:This study was a single-center prospective study,according to random number table method,129 neonatal with RDS who were admitted to our hospital from January 2022 to October 2024 were divided into control group(received pressure-controlled ventilation,n=64)and observation group(received pressure-controlled ventilation combined with VG,n=65).The duration of invasive ventilation,total duration of respiratory support,length of hospital stay,arterial blood gas parameters[partial pressure of carbon dioxide(PaCO2),pH value,partial pressure of oxygen(PaO2),PaO2/fraction of inspired oxygen(FiO2)],weaning time,extubation failure rate and incidence of complications were compared between the two groups.Results:The duration of invasive ventilation,the total duration of respiratory support,the weaning time and the length of hospital stay in the observation group were shorter than those in the control group,and the extubation failure rate and the incidence of complications were lower than those in the control group(P＜0.05).24 h,48 h after intervention,PaCO2 decreased,while pH value,PaO2 and PaO2/FiO2 increased.The PaCO2 in the observation group was lower than that in the control group,while the pH value,PaO2 and PaO2/FiO2 were higher than those in the control group(P＜0.05).Conclusion:Mechanical ventilation based on VG can shorten the mechanical ventilation time of neonatal with RDS,improve blood gas analysis indicators,and reduce weaning time,extubation failure rate and the risk of complications.
